KDM5B protein-GST fusion
Product Sizes
20 ug
£431.00
010-001-S36S-20UG
About this Product
- SKU:
- 010-001-S36S
- Additional Names:
- Jarid1b,PUT1,Plu1,PLU-1,Rb-Bp2, AW556288, RBBP2H1A, mKIAA4034, Lysine-specific demethylase 5B, EC 1.14.11.-, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, PLU-1|Kdm5b
- Application:
- Western Blot
- Buffer:
- See application note.
- CE/IVD:
- RUO
- Concentration:
- 0.1 ug/ul
- Extra Details:
- KDM5B is a lysine (K)-specific demethylase 5B which is highly expressed in testis and shows the lowest expression in skeletal muscle (1). KDM5B is a histone H3 lysine 4 (H3K4) demethylase up-regulated in prostate cancer and associated with androgen receptor where it regulated its transcriptional activity in reporter gene assays (2). Overexpression of KDM5B in HeLa cells results in loss of tri-, di-, and monomethyl H3K4, but does not alter the methylation status of H3K9 or H3K36. A KDM5B containing highly conserved putative DNA/chromatin binding motif is specifically up-regulated in breast cancer. KDM5B Protein is ideal for investigators involved in Signaling Proteins, Deacetylase/Demethylase Proteins, Cancer, Cell Cycle, and Inflammation research.
- Immunogen:
- Kdm5b
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Specificity:
- Recombinant mouse KDM5B (1-753) was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >90% by densitometry.
- Storage Conditions:
- -70[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=010-001-S36S
