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Proteins and Peptides

rHuman IL-4 Protein

Product Sizes
100 ug
009-F01-B93-0100-100UG
About this Product
SKU:
009-F01-B93-0100
Additional Names:
B cell Stimulating Factor (BSF-1), Binetrakin, BCDF, BCGF, Lymphocyte stimulatory factor 1, Pitrakinra|IL4
Application:
Cell-based/Functional Assay
Buffer:
0.1% Trifluoroacetic acid
CE/IVD:
RUO
Extra Details:
Interleukin-4 (IL-4) is an immuno-modulatory cytokine, produced primarily by a subgroup of helper T cells, known as Th2. IL-4 is known to induce naive helper T cells to differentiate to Th2 cells, which subsequently produce more IL-4. Th2 cells regulate a wide variety of other immune cells including, B cells, where it has the ability to promote IgG to IgE isotype switching. Recombinant human IL-4 is a non-glycosylated protein, containing 130 amino acids, with a molecular weight of 15 kDa.
Formulation:
0.1% Trifluoroacetic acid
Immunogen:
IL4
Physical State:
Lyophilized
Purity:
>98%
Shipping Conditions:
Ambient
Specificity:
Interleukin-4 is produced with no animal-derived raw products, animal free equipment and animal free protocols. Purity was determined to be greater than 98% as determined by HPLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-PAGE.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Bioactivity of Human Interleukin-4 Recombinant Protein . TF-1 cells were cultured with 0 to 10 ng/mL Human IL-4. Cell proliferation was measured after 72 hours and the linear portion of the curve was us used to calculate the ED50. The ED50 of Human IL-4 is 0.16-0.24 ng/mL. This value is comparable to expected range of less than 0.2 ng/mL.