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Antibodies

Human IgA Biotin

Product Sizes
1 mg
£234.00
009-0606-1MG
About this Product
SKU:
009-0606
Additional Names:
Human IgA Whole Molecule Biotin Conjugate
Application:
Microarray
Buffer:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
CE/IVD:
RUO
Conjugate:
Biotin
Concentration:
1 mg/ml
Extra Details:
Immunoglobulin A is the primary responder in muscosal immunity, and comprises close to 75% of the total immunoglobulin produced. IgA can also be secreted and is protected from degradation by many proteolytic enzymes (which allows it to be secreted along the gastrointestinal tract). Immunoglobulin A only weakly activates the complement system and is not readily opsonized.
Formulation:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Isotype:
IgA
Physical State:
Lyophilized
Shipping Conditions:
Ambient
Specificity:
This product was prepared from normal serum by delipidation, salt fractionation, ion exchange chromatography followed by extensive dialysis against the buffer stated above. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-biotin, anti-Human IgA (a chain specific) and anti-Human Serum. No reaction was observed against anti-Human IgG F(c) or anti-Human IgM (Fc5u).
Storage Conditions:
2-8[o]C liquid. Aliquot. Avoid freeze/thaw cycles., -20[o]C/-70[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Antibody: Isotype Controls
SARS-CoV-2 N protein amino acid coverage on SARS-CoV-2 microarray. (A) Final N protein constructs fabricated on the SARS-CoV-2 microarray, including the full-length protein, core domain (amino acids 44-362), N-terminal domain (NTD) (amino acids 43-179), C-terminal domain (CTD) (amino acids 246-363), peptide 6 (amino acids 395-412), peptide 8 (amino acids 211-228) and peptide 16 (amino acids 367-389). (B) Final microarray layout: 24-plex array with 16 probes (summarized in the Table insert) printed in triplicate. Control antigens used in the microarray included 50 ug/mL of biotinylated human immunoglobulins G, A, and M (hIgG, hIgA, and hIgM, respectively; Rockland, Gilbertsville, PA, USA) and 132 ug/mL of biotinylated anti-human immunoglobulin G (anti-hIgG; Rockland) as well as in house derivatized NHS-ester-Cy3 (Thermo Scientific) biotinylated BSA (Cy3-BSA) at 40 ug/mL. Figure S2. PMID: 33925055.