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Proteins and Peptides

rHuman Visfatin Protein

Product Sizes
5 ug
£184.00
009-001-W40-0005-5UG
About this Product
SKU:
009-001-W40-0005
Additional Names:
NAMPT|Pre-B-cell colony-enhancing factor 1, PBEF
Application:
Cell-based/Functional Assay, SDS-PAGE
Buffer:
0.1% Trifluoroacetic acid
CE/IVD:
RUO
Extra Details:
Visfatin is an adipokine produced by visceral adipose tissue. Other adipokines include leptin, adiponectin, resistin, chemerin, omentin and vaspin. Visfatin has been shown to act as a pro-inflammatory factor for PBMCs and may mimic the effects of insulin on adipocytes, monocytes and hepatocytes. Recombinant human Visfatin is a non-glycosylated protein, containing 466 amino acids, with a molecular weight of 52.6 kDa.
Formulation:
0.1% Trifluoroacetic acid
Immunogen:
NAMPT
Physical State:
Lyophilized
Purity:
>90%
Shipping Conditions:
Ambient
Specificity:
Visfatin purity was determined to be greater than 90% as determined by reducing and non-reducing SDS-pAGE.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
SDS-PAGE of Human Visfatin Recombinant Protein. Lane 1: 1 ug Human Visfatin in reducing conditions (+). Lane 2: Molecular weight marker. Lane 3: 1 ug Human Visfatin in non-reducing conditions (-). Human Visfatin has a predicted MW of 52.6 kDa.
Bioactivity of Human Visfatin Recombinant Protein. 100 ng/mL Human Visfatin was added to cultures of healthy human PBMCs. After 6 and 24 hours, IL-6 expression was measured (RNA). LPS was used as a positive control. A significant increase in IL-6, TNFa and IL-1 beta were seen at 6 and 24 hours. Only IL-6 is shown, but other data is available by request.