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Proteins and Peptides

rHuman TGF beta1 Protein

Product Sizes
5 ug
£155.00
009-001-W26-0005-5UG
About this Product
SKU:
009-001-W26-0005
Additional Names:
Differentiation inhibiting factor, cartilage-inducing factor|TGFB1
Application:
Cell-based/Functional Assay
Buffer:
0.1% Trifluoroacetic acid
CE/IVD:
RUO
Concentration:
0.1 mg/ml
Extra Details:
Transforming Growth Factor-beta 1 (TGF-B Beta1) is a member of the TGF-beta superfamily. Members of this family are known to exhibit regulatory activity in immunity and proliferation pathways. TGF-B Beta1 signals through SMAD proteins via the TGF-B Beta1 RI and RII receptors. Mature human TGF-B Beta1 is a glycosylated homodimer, containing two 112 amino acids chains, with a total molecular weight of 25 kDa.
Formulation:
0.1% Trifluoroacetic acid
Immunogen:
TGFB1
Physical State:
Lyophilized
Purity:
>98%
Shipping Conditions:
Ambient
Specificity:
Transforming Growth Factor beta 1 purity was determined to be greater than 98% as determined by reducing and non-reducing SDS-pAGE.
Storage Conditions:
-20[o]C with carrier protein. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Bioactivity of Human Transforming Growth Factor beta 1 Recombinant Protein. Serial dilutions of Human TGF-Beta 1 (starting at 10 ng/mL) were added to HT-2 cultured with IL-4. Cell proliferation was measured and the linear portion of the curve was us used to calculate the ED50. The ED50 of Human TGF-Beta 1 is between 0.1-0.15 ng/mL. This is comparable to the expected range of 0.04-0.2 ng/mL for this assay.