Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Proteins and Peptides

rHuman M-CSF Protein

Product Sizes
100 ug
£919.00
009-001-V78-0100-100UG
About this Product
SKU:
009-001-V78-0100
Additional Names:
CSF1|MGI-IM, Lanimostim
Application:
Cell-based/Functional Assay, SDS-PAGE
Buffer:
See application note.
CE/IVD:
RUO
Extra Details:
Macrophage Colony Stimulating Factor (M-CSF) is a hematopoietic growth factor produced by a wide variety of cells. M-CSF is known to stimulate differentiation of hematopoietic stem cells to monocyte-macrophage cell populations in culture. M-CSF acts through the CSF receptor 1. Although human M-CSF shows activity on mouse cells, mouse CSF shows no activity on human cells. Recombinant human M-CSF is a disulfide linked homodimer, containing two 159 amino acid chains, with a total molecular weight of 36.8 kDa.
Immunogen:
CSF1
Physical State:
Lyophilized
Purity:
>97%
Shipping Conditions:
Ambient
Specificity:
Macrophage Colony Stimulating Factor purity was determined to be greater than 97% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
SDS-PAGE of Human Macrophage Colony Stimulating Factor Recombinant Protein. Lane 1: 1 ug Human M-CSF in non-reducing conditions (-). Lane 2: 1 ug Human M-CSF in reducing conditions (+). Lane 3: Molecular weight marker. Human M-CSF is a homodimer with a total predicted MW of 36.8 kDa.
Bioactivity of Human Macrophage Colony Stimulating Factor Recombinant Protein. Serial dilutions of Human M-CSF, starting at 50 ng/mL, were added to NSF-60 cells. Cell proliferation was measured after 68 hours and the linear portion of the curve was us used to calculate the ED50. The ED50 of Human M-CSF is 1.4-2.1 ng/mL. This value is comparable with the typical expected range of less than 2 ng/mL.