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Proteins and Peptides

rHuman CCL7 Protein

Product Sizes
100 ug
£728.00
009-001-V76-0100-100UG
About this Product
SKU:
009-001-V76-0100
Additional Names:
CCL7, MARC|MCP-3
Application:
Cell-based/Functional Assay, SDS-PAGE
Buffer:
0.1% Trifluoroacetic acid
CE/IVD:
RUO
Extra Details:
Monocyte Chemotactic Protein 3 (MCP-3), also called CCL7, is produced by macrophages and some tumor cell lines. MCP-3 signals through three different G protein-coupled receptors, CCR1, CCR2, and CCR3. CCL7 chemoattracts monocytes and can regulate macrophage function. Recombinant human MCP-3 is a non-glycosylated protein, containing 76 amino acids, with a molecular weight of 9 kDa.
Formulation:
0.1% Trifluoroacetic acid
Immunogen:
MCP-3
Physical State:
Lyophilized
Purity:
>98%
Shipping Conditions:
Ambient
Specificity:
Monocyte Chemotactic protein-3 (CCL7) purity was determined to be greater than 98% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
SDS-PAGE of Human Monocyte Chemotactic Protein-3 (CCL7) Recombinant Protein. Lane 1: 1 ug Human MCP-3 in non-reducing conditions (-). Lane 2: 1 ug Human MCP-3 in reducing conditions (+). Lane 3: Molecular weight marker. Human MCP-3 has a predicted MW of 9 kDa.
Bioactivity of Human Monocyte Chemotactic Protein-3 (CCL7) Recombinant Protein. Triplicate samples of primary human neutrophils from three donors were allowed to migrate to Human MCP-3 (10, 100 and 1000 ng/mL). After 30 minutes, cells that migrated were counted using a luminescent substrate and displayed on the bar graph above. Significant levels of migration over basal were seen in response to Human MCP-3/CCL7 starting at 10 ng/mL.