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Proteins and Peptides

rHuman IL-17E (IL-25) Protein

Product Sizes
100 ug
009-001-V57-0100-100UG
About this Product
SKU:
009-001-V57-0100
Additional Names:
IL17E|IL25
Application:
Cell-based/Functional Assay, SDS-PAGE
Buffer:
0.1% Trifluoroacetic acid
CE/IVD:
RUO
Extra Details:
Interleukin-17E (IL-17E), also commonly called IL-25, is a pro-inflammatory cytokine member of a six-species family of proteins (IL-17A-17F). IL-17F stimulates secretion of IL-8 and induces activation of NF-kB by binding to the receptor IL-17RB. Recombinant human IL-17E is a non-glycosylated, disulfide-linked, homodimer, containing two 145 amino acid chains, with a total molecular weight of 35.5 kDa.
Formulation:
0.1% Trifluoroacetic acid
Immunogen:
IL25
Physical State:
Lyophilized
Purity:
>95%
Shipping Conditions:
Ambient
Specificity:
Interleukin-17E (IL-25) purity was determined to be greater than 95% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
SDS-PAGE of Human Interleukin-17E (IL-25) Recombinant Protein. Lane 1: 1 ug Human IL-17E in non-reducing conditions (-). Lane 2: Molecular weight marker. Human IL-17E is a homodimer with a predicted total MW of 33.8 kDa.
Bioactivity of Human Interleukin-17E (IL-25) Recombinant Protein. Human PBMCs were cultured with 0 to 1000 ng/mL Human IL-17E. Human IL-8 production was measured after 48 hours and the linear portion of the curve was us used to calculate the ED50. The ED50 of Human IL-17E is 62-94 ng/mL. This value is comparable to the expected range of 10-100 ng/mL.