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Proteins and Peptides

rHuman IL-16 Protein

Product Sizes
100 ug
£1087.00
009-001-V55-0100-100UG
About this Product
SKU:
009-001-V55-0100
Additional Names:
IL16|Lymphocyte Chemoattractant Factor (LCF)
Application:
Cell-based/Functional Assay, SDS-PAGE
Buffer:
0.01 M Sodium Phosphate
CE/IVD:
RUO
Extra Details:
Interleukin 16 (IL-16) is produced primarily by CD4+ and CD8+ T cells and acts as a chemo-attractant for lymphocytes, monocytes, eosinophils, dendritic cells and Langerhans cells. Additionally, IL-16 has been reported to upregulate IL-2 receptor (CD25), induce progression of cells to the G1 phase and suppress HIV & SIV replication. Recombinant human IL-16 is a non-glycosylated protein, containing130 amino acids, with a molecular weight of 13.5 kDa.
Formulation:
0.01 M Sodium Phosphate, pH 7.5
Immunogen:
IL16
Physical State:
Lyophilized
Purity:
>95%
Shipping Conditions:
Ambient
Specificity:
Interleukin-16 purity was determined to be greater than 95% as determined by analysis by UV-Spectroscopy at 280nm and by reducing and non-reducing SDS-pAGE.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
SDS-PAGE of Human Interleukin-16 Recombinant Protein. Lane 1: Molecular weight marker. Lane 2: 1 ug Human IL-16 in non-reducing conditions (-). Lane 3: Molecular weight marker. Lane 4: 1 ug Human IL-16 in reducing conditions (+). Human IL-16 has a predicted MW of 12.5 kDa.
Bioactivity of Human Interleukin-16 Recombinant Protein. Human T cells were allowed to migrate to Human IL-16 at (0, 5, 20, 100 and 500 ng/mL). After 4 hours, cells that migrated were counted using a luminescent substrate and displayed on the bar graph above. A significant increase in migration over basal levels was seen in response to Human IL-16 starting at 5 ng/mL.