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Proteins and Peptides

rHuman IL-11 Protein

Product Sizes
100 ug
009-001-V49-0100-100UG
About this Product
SKU:
009-001-V49-0100
Additional Names:
AGIF (Adipogenesis Inhibitory Factor), Oprelvekin|IL11
Application:
Cell-based/Functional Assay, SDS-PAGE
Buffer:
0.1% Trifluoroacetic acid
CE/IVD:
RUO
Extra Details:
Interleukin 11 (IL-11) is a pleotropic cytokine closely related to IL-6 in function, but is overall one of the lesser characterized interleukins. In hematopoietic cell populations, IL-11 is thought to induce megakaryocyte differentiation. In non-hematopoietic populations, IL-11 is thought to be able to stimulate hepatic acute-phase proteins. Human IL-11 can stimulate murine cells. Recombinant human IL-11 is a non-glycosylated protein, containing 179 amino acids, with a molecular weight of 19.3 kDa.
Formulation:
0.1% Trifluoroacetic acid
Immunogen:
IL11
Physical State:
Lyophilized
Purity:
>95%
Shipping Conditions:
Ambient
Specificity:
Interleukin-11 purity was determined to be greater than 95% as determined by analysis by UV-Spectroscopy at 280nm and by reducing and non-reducing SDS-pAGE.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
SDS-PAGE of Human Interleukin-11 Recombinant Protein. Lane 1: 1 ug Human IL-11 in non-reducing conditions (-). Lane 2: 1 ug Human IL-11 in reducing conditions (+). Lane 3: Molecular weight marker. Human IL-11 has a predicted MW of 19 kDa.
Bioactivity of Human Interleukin-11 Recombinant Protein. Serial dilutions of Human IL-11 (starting at 100 ng/mL) were added to T-11 cells growing the presence of 2 ng/mL IL-6. After 91 hours, cell proliferation was measured and the linear portion of the curve was us used to calculate the ED50. The ED50 of Human IL-11 is between 0.35-0.52 ng/mL. This value is comparable to the typically expected to be less than 2 ng/mL.