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Proteins and Peptides

rHuman GDF-15 (D variant) Protein

Product Sizes
100 ug
£800.00
009-001-V09-0100-100UG
About this Product
SKU:
009-001-V09-0100
Additional Names:
GDF15|Macrophage inhibitory cytokine 1 (MIC-1), NSAID-activated gene 1 protein (NAG-1), NSAID-regulated gene 1 protein (NRG-1), Placental TGFB Beta, Placental bone morphogenetic protein, Prostate differentiation factor
Application:
SDS-PAGE
Buffer:
0.1% Trifluoroacetic acid
CE/IVD:
RUO
Extra Details:
Growth and Differentiation Factor 15 (GDF-15) is a TGFB Beta family member, made by the placenta and heart tissues, that has a role in regulating inflammatory and apoptotic pathways. GDF-15 has become an immerging marker of early heart disease and has the potential as being used as a molecule for screening patients for early heart failure. Recombinant human GDF-15 D is a non-glycosylated, disulfide linked homodimer, containing two identical 113 amino acid chains, with a total molecular weight of 24.5 kDa. There is a His to an Asp substitution at position 7.
Formulation:
0.1% Trifluoroacetic acid
Immunogen:
GDF15
Physical State:
Lyophilized
Purity:
>95%
Shipping Conditions:
Ambient
Specificity:
Growth and Differentiation Factor-15 (D variant) purity was determined to be greater than 95% as determined by analysis by HpLC, UV-Spectroscopy at 280nm and by reducing and non-reducing SDS-pAGE.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
SDS-PAGE of Human Growth and Differentiation Factor-15 (D variant) Recombinant Protein. Lane 1: 1 ug Human GDF-15 D Variant in non-reducing conditions (-). Lane 2: Molecular weight marker. Lane 3: 1 ug Human GDF-15 D Variant in reducing conditions (+). Lane 4: Molecular weight marker. Human GDF-15 D Variant is predicted to be a homodimer with a predicted MW of 24.5 kDa.