VLK protein-GST fusion
Product Sizes
20 ug
£431.00
009-001-U57S-20UG
About this Product
- SKU:
- 009-001-U57S
- Additional Names:
- PKDCC|SGK493, PKDCC, Protein kinase domain-containing protein, cytoplasmic, Protein kinase-like protein SgK493, Sugen kinase 493, Vertebrate lonesome kinase
- Application:
- Western Blot
- Buffer:
- See application note.
- CE/IVD:
- RUO
- Concentration:
- 0.05 ug/ul
- Extra Details:
- VLK or vertebrate lonesome kinase is a protein kinase which is first expressed in E-cadherin-positive anterior visceral endoderm and mesendoderm, and later its expression is confined to E-cadherin-negative mesenchyme. VLK regulates the rate of protein export from the Golgi and thereby plays an important role in the formation of functional stroma by mesenchymal cells (1). Targeted disruption of VLK leads to a defect in lung development and delayed ossification of endochondral bone. VLK deficient mice display neonatal lethality due to respiratory failure, with a suckling defect arising from a cleft palate. VLK is required for the appropriate timing of flat proliferative chondrocyte differentiation (2). VLK Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Cancer, Cytoplasmic Tyrosine Kinases, Invasion/Metastasis, Neurobiology, and Ser/Thr Kinases research.
- Immunogen:
- PKDCC
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Specificity:
- Recombinant human VLK (129-end) was expressed by baculovirus in Sf9 insect cells using an N-Terminal his epitope. The purity was determined to be >70% by densitometry.
- Storage Conditions:
- -70[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=009-001-U57S
