UBLE1A (SAE1) protein-GST fusion
Product Sizes
20 ug
£415.00
009-001-U49S-20UG
About this Product
- SKU:
- 009-001-U49S
- Additional Names:
- SAE1|SAE1, SUA1, HSPC140, AOS1, FLJ3091, HSPC140, SUMO-activating enzyme subunit 1
- Application:
- Western Blot
- Buffer:
- See application note.
- CE/IVD:
- RUO
- Concentration:
- 0.1 ug/ul
- Extra Details:
- UBLE1A (also known as SAE1) or SUMO1 activating enzyme subunit 1 is involved in regulating protein structure and intracellular localization. SAE1 and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (1). The SAE1/SAE2 dimer functions in SUMO1 activation in a manner analogous to the single E1 ubiquitin-activating enzymes. The SAE2 inactivation may be a therapeutic strategy in MYC-driven cancers (2). UBLE1A Protein is ideal for investigators involved in Signaling Proteins, Ubiquitin Proteins, Cancer, Cell Cycle, and Neurobiology research.
- Immunogen:
- SAE1
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Specificity:
- Recombinant full-length human UBLE1A (SAE1) was expressed by E. coli cells using an N-terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >95% by densitometry.
- Storage Conditions:
- -70[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=009-001-U49S
