UBA2 (SAE2) protein-GST fusion
Product Sizes
20 ug
£415.00
009-001-U25S-20UG
About this Product
- SKU:
- 009-001-U25S
- Additional Names:
- UBA2|UBA2, UBLE1B, SAE2, ARX, HRIHFB2115, SUMO-activating enzyme subunit 2
- Application:
- Western Blot
- Buffer:
- See application note.
- CE/IVD:
- RUO
- Concentration:
- 0.1 ug/ul
- Extra Details:
- UBA2 (SAE2) or ubiquitin-like modifier activating enzyme 2 forms a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins. The posttranslational modification of proteins by the addition of the small protein SUMO, or sumoylation, regulates protein structure and intracellular localization (1). UBA2 functions in SUMO1 activation in a manner analogous to the single E1 ubiquitin-activating enzymes (2). The inactivation of UBA2 may be a therapeutic strategy in MYC-driven cancers. UBA2 Protein is ideal for investigators involved in Signaling Proteins, Ubiquitin Proteins, Cancer, Cell Cycle, and Neurobiology research.
- Immunogen:
- UBA2
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Specificity:
- Recombinant full-length human UBA2 (SAE2) was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >85% by densitometry.
- Storage Conditions:
- -70[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=009-001-U25S
