TRDMT1 (DNMT2) protein-GST fusion
Product Sizes
20 ug
£431.00
009-001-U19S-20UG
About this Product
- SKU:
- 009-001-U19S
- Additional Names:
- DNMT2, DMNT2, PUMET, RNMT1, MHSAIIP, tRNA (cytosine(38)-C(5))-methyltransferase, DNA (cytosine-5)-methyltransferase-like protein 2, Dnmt2|TRDMT1
- Application:
- Western Blot
- Buffer:
- See application note.
- CE/IVD:
- RUO
- Concentration:
- 0.1 ug/ul
- Extra Details:
- TRDMT1 is responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. TRDMT1 also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, TRDMT1 is distinct and highly conserved in its function among various species. The indirect sequence recognition is also a feature of eukaryotic DNA methyltransferases, which may have arisen from a DNMT2-like RNA methyltransferase (1). DNMT2 is involved in retrotransposon silencing and telomere integrity in somatic cells (2). TRDMT1 Protein is ideal for investigators involved in Signaling Proteins, Acetyl/Methyltransferase Proteins, Apoptosis/Autophagy, Cancer, Cell Cycle, and Neurobiology research.
- Immunogen:
- TRDMT1
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Specificity:
- Recombinant full-length human TRDMT1 (DNMT2) was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >95% by densitometry.
- Storage Conditions:
- -70[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=009-001-U19S
