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Proteins and Peptides

STK11 protein-GST fusion

Product Sizes
20 ug
£431.00
009-001-T60S-20UG
About this Product
SKU:
009-001-T60S
Additional Names:
STK11|STK11, LKB1, PJS, Serine/threonine-protein kinase STK11, Renal carcinoma antigen NY-REN-19
Application:
Western Blot
Buffer:
See application note.
CE/IVD:
RUO
Concentration:
0.2 ug/ul
Extra Details:
LKB1 (STK11) is a member of the serine/threonine kinase family which regulates cell polarity and functions as a tumor suppressor. STK11 is a critical barrier to pulmonary tumorigenesis which controlling initiation, differentiation, and metastasis. STK11 plays a central role in restricting HSC entry into cell cycle and in broadly maintaining energy homeostasis in hematopoietic cells through a novel metabolic checkpoint (1). STK11 serves as an essential regulator of HSCs and hematopoiesis, and more generally, points to the critical importance of coupling energy metabolism and stem cell homeostasis (2). SKT11 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Apoptosis/Autophagy, Cancer, Cellular Stress, Metabolic Disorder, and Ser/Thr Kinases research.
Immunogen:
STK11
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Specificity:
Recombinant full-length human LKB1 (STK11) was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >90% by densitometry.
Storage Conditions:
-70[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes