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Proteins and Peptides

STAT6 protein-GST fusion

Product Sizes
20 ug
£457.00
009-001-T57S-20UG
About this Product
SKU:
009-001-T57S
Additional Names:
STAT6|STAT6B, STAT6C, D12S1644, IL-4-STAT, Signal transducer and activator of transcription 6 (IL-4 Stat)
Application:
Western Blot
Buffer:
See application note.
CE/IVD:
RUO
Concentration:
0.2 ug/ul
Extra Details:
The STAT6 protein is a member of the STAT family of transcription factors that are activated by cytokines and phosphorylated by the receptor associated kinases. STATs form homo- or hetero-dimers that translocate to the cell nucleus where they act as transcription activators (1). STAT6 plays a central role in exerting IL4 mediated biological responses. STAT6 induces the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. STAT6 mRNA has been detected in various tissues including peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response (2). STAT6 Protein is ideal for investigators involved in Signaling Proteins, Transcription Proteins, Apoptosis/Autophagy, Cancer, ERK/MAPK Pathway, Inflammation, and JAK/STAT Pathway research.
Immunogen:
STAT6
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Specificity:
Full-length recombinant human STAT6 was expressed in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >80% by densitometry.
Storage Conditions:
-70[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins