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Proteins and Peptides

SETMAR protein-GST fusion

Product Sizes
20 ug
£431.00
009-001-T30S-20UG
About this Product
SKU:
009-001-T30S
Additional Names:
METNASE, Histone-lysine N-methyltransferase SETMAR, HsMar1, Histone-lysine N-methyltransferase, Mariner transposase Hsmar1|SETMAR
Application:
Western Blot
Buffer:
See application note.
CE/IVD:
RUO
Concentration:
0.2 ug/ul
Extra Details:
SETMAR or SET domain and mariner transposase fusion gene is a nonhomologous end-joining repair protein that regulates genomic integration of exogenous DNA by opening chromatin and facilitating joining of DNA ends (1). SETMAR has histone methyltransferase activity and methylates 'Lys-4' and 'Lys-36' of histone H3. SETMAR also has DNA nicking activity and may play a role in DNA repair (2). Human Pso4 forms a stable complex with SETMAR that regulates Metnase function in DNA repair. SETMAR has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. SETMAR Protein is ideal for investigators involved in Signaling Proteins, Acetyl/Methyltransferase Proteins, Apoptosis/Autophagy, Cancer, Cell Cycle, and Neurobiology research.
Immunogen:
SETMAR
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Specificity:
Recombinant full-length human SETMAR was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >85% by densitometry.
Storage Conditions:
-70[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes