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Proteins and Peptides

P300 protein-GST fusion

Product Sizes
20 ug
£457.00
009-001-S63S-20UG
About this Product
SKU:
009-001-S63S
Additional Names:
EP300|EP300, KAT3B, Histone acetyltransferase p300
Application:
Western Blot
Buffer:
See application note.
CE/IVD:
RUO
Concentration:
0.2 ug/ul
Extra Details:
P300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein (1). P300 is related by sequence to CBP and like CBP can stimulate transcription through activation of CREB. The P300 activity is specifically inhibited by the adenovirus oncoprotein E1A. P300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. P300 is a components of DRAF1 (double-stranded RNA-activated factor-1), a positive regulator of interferon-stimulated gene transcription that functions as a direct response to viral infection (2). P300 Protein is ideal for investigators involved in Signaling Proteins, Acetyl/Methyltransferase Proteins, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cell Cycle, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Metabolic Disorder, Neurobiology, NfkB Pathway, and PKA/PKC Pathway research.
Immunogen:
EP300
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Specificity:
Recombinant human P300 (1283-1673) was expressed in Sf9 cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >90% by densitometry.
Storage Conditions:
-70[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes