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Proteins and Peptides

Mortalin protein-GST fusion

Product Sizes
20 ug
£431.00
009-001-S51S-20UG
About this Product
SKU:
009-001-S51S
Additional Names:
HSPA9|HSPA9, CSA, GRP75, HSPA9B, MGC4500, MOT, mot-2, MOT2, MTHSP75, PBP74, Stress-70 protein, mitochondrial 75 kDa glucose-regulated protein, GRP-75, Heat shock 70 kDa protein 9, Mortalin, MOT, Peptide-binding protein 74, PBP74
Application:
Western Blot
Buffer:
See application note.
CE/IVD:
RUO
Concentration:
0.2 mg/ml
Extra Details:
Mortalin is a mitochondrial chaperone and a member of the heat shock protein 70 family that is constitutively expressed in cells. Mortalin plays a central role in mitochondrial biogenesis through its capacity to direct the import of nuclear-encoded proteins into the mitochondria. Mortalin plays a role in the control of cell proliferation and elevated levels of mortalin have correlated with malignant transformation and poor cancer prognosis. Mortalin can support cancer cell resistance to complement-dependent cytotoxicity (1). Mortalin expression was decreased in the mitochondrial fraction of neurons from the substantia nigra of Parkinson disease patients (2). Mortalin Protein is ideal for investigators involved in Signaling Proteins, Cell Stress & Chaperone Proteins, Apoptosis/Autophagy, and Cancer research.
Immunogen:
HSPA9
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Specificity:
Recombinant human Mortalin (47-end) protein was expressed in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >80% by densitometry.
Storage Conditions:
-70[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins