CDKN3 protein-GST fusion
Product Sizes
20 ug
£431.00
009-001-R70S-20UG
About this Product
- SKU:
- 009-001-R70S
- Additional Names:
- CDI1, CIP2, FLJ25787, KAP, KAP1, MGC70625, Cyclin-dependent kinase inhibitor 3, CDK2-associated dual-specificity phosphatase, Cyclin-dependent kinase interactor 1 , Cyclin-dependent kinase-interacting protein 2, Kinase-associated phosphatase|CDKN3
- Application:
- Western Blot
- Buffer:
- See application note.
- CE/IVD:
- RUO
- Concentration:
- 0.2 ug/ul
- Extra Details:
- CDKN3 is a member of the dual specificity protein phosphatase family that acts as a cyclin-dependent kinase inhibitor (1). CDKN3 has been shown to interact with and dephosphorylate specifically the CDK2 kinase thereby preventing it's activation. CDKN3 has been reported to be deleted, mutated, or overexpressed in several kinds of cancers. Increased expression of CDKN3 leads to increased levels of kinase-associated phosphatase activity that inhibits the G(1)/S transition of the cell cycle by dephosphorylating the cyclin-dependent kinases (2). CDKN3 Protein is ideal for investigators involved in Signaling Proteins, Cell Cycle Proteins, Cancer, Cell Cycle, and Ser/Thr Kinases research.
- Immunogen:
- CDKN3
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Specificity:
- Recombinant full-length human CDKN3 was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >90% by densitometry.
- Storage Conditions:
- -70[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=009-001-R70S
