BCR protein-GST fusion
Product Sizes
20 ug
£431.00
009-001-R50S-20UG
About this Product
- SKU:
- 009-001-R50S
- Additional Names:
- ALL, CML, PHL, BCR1, D22S11, D22S662, FLJ1645, Breakpoint cluster region protein, Renal carcinoma antigen NY-REN-26, BCR, BCR1, D22S11|BCR
- Application:
- Western Blot
- Buffer:
- See application note.
- CE/IVD:
- RUO
- Concentration:
- 0.2 ug/ul
- Extra Details:
- BCR (also known as breakpoint cluster region) encodes a phosphoprotein that has serine/threonine kinase activity (1). The human c-ABL oncogene is translocated from chromosome 9 to a region on chromosome 22 (associated with BCR) in chronic myelocytic leukemia. In classical t(9;22) translocation, as observed in chronic granulocytic leukemia (CGL), a hybrid DNA unit is produced comprising the BCR gene product plus the translocated c-ABL gene from chromosome 9. The BCR-ABL hybrid protein (p210) is formed that displays increased tyrosine kinase activity. A similar DNA rearrangement of the p210 protein is also found in cases of Philadelphia-positive acute lymphoblastic leukemia (ALL) (2). BCR Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, and Cancer research.
- Immunogen:
- BCR
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Specificity:
- Recombinant human BCR (1-695) was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >75% by densitometry.
- Storage Conditions:
- -70[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=009-001-R50S
