Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Proteins and Peptides

rHuman Fractalkine (CX3CL1) Protein

Product Sizes
100 ug
009-001-H49-0100-100UG
About this Product
SKU:
009-001-H49-0100
Additional Names:
C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1|CX3CL1
Application:
Cell-based/Functional Assay
Buffer:
0.1% Trifluoroacetic acid
CE/IVD:
RUO
Extra Details:
Fractalkine, also known as CX3CL1, is an atypical chemokine that was the first of a fourth chemokine motif (CX3C). It is thought to function as a T cell and monocyte chemotractant and is produced by non-haemopoietic cells. Fractalkine is made in a soluble and membrane bound form in activated endothelial cells which is thought to promote adhesion of leukocytes. Recombinant human Fractalkine is a non-glycosylated protein, containing 76 amino acids, with a molecular weight of 8.6 kDa.
Formulation:
0.1% Trifluoroacetic acid
Immunogen:
CX3CL1
Physical State:
Lyophilized
Purity:
>98%
Shipping Conditions:
Ambient
Specificity:
Fractalkine (CX3CL1) purity was determined to be greater than 98% as determined by analysis by HpLC, UV-Spectroscopy at 280nm and by reducing and non-reducing SDS-pAGE.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Bioactivity of Human Fractalkine (CX3CL1) Recombinant Protein. Human PBMCs were allowed to migrate to Human Fractalkine at (0, 0.1, 1, 10 , 100 and 1000 ng/mL). After 4 hours, cells that migrated were counted using a luminescent substrate and displayed on the bar graph above. Significant increases in migration over basal levels were seen in response to Human Fractalkine detectable starting at between 10-100 ng/mL.