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Proteins and Peptides

SOD2 protein-GST fusion

Product Sizes
20 ug
£415.00
009-001-G14S-20UG
About this Product
SKU:
009-001-G14S
Additional Names:
Mn-SOD, MNSOD, IPO-B, Superoxide Dismutase 2|SOD2
Application:
Western Blot
Buffer:
See application note.
CE/IVD:
RUO
Concentration:
0.2 ug/ul
Extra Details:
SOD2 (superoxide dismutase 2) is a member of the iron/manganese superoxide dismutase family. SOD2 binds to the superoxide byproducts of the mitochondrial electron transport chain and converts them to hydrogen peroxide and diatomic oxygen. Failure of SOD2 to remove the superoxide byproducts leads to an increase in mitochondrial reactive oxygen species resulting in biochemical aberrations with features reminiscent of mitochondrial myopathy, Friedreich ataxia, and HMGCL deficiency (1). Mutations in SOD2 have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer (2). SOD2 Protein is ideal for investigators involved in Signaling Proteins, Cell Stress & Chaperone Proteins, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cellular Stress, Inflammation, Neurobiology, and p38 Pathway research.
Immunogen:
SOD2
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Specificity:
Recombinant full-length human SOD2 was expressed in E. coli cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >90% by densitometry.
Storage Conditions:
-70[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes