IL-1 Beta Human Recombinant Protein
Product Sizes
10 ug
£319.00
009-001-301-10UG
About this Product
- SKU:
- 009-001-301
- Additional Names:
- IL-1b cytokine, Interleukin 1b, IL-1B Beta, IL-1 beta, Catabolin, H1, Hematopoietin 1, IFN beta inducing factor, Interleukin 1 beta, LAF, OAF, Osteoclast activating factor|IL1B
- Application:
- SDS-PAGE
- Buffer:
- 0.01 M Sodium Phosphate
- CE/IVD:
- RUO
- Concentration:
- 0.1 mg/ml
- Extra Details:
- Interleukin-1beta (IL-1B Beta) is a proinflammatory cytokine produced in response to inflammatory agents by a variety of cells, including monocytes, macrophages, and dendric cells (DCs). IL-1B Beta and IL-1A Alpha are two distinct and independently regulated gene products that comprise IL-1 and signal through the Type 1 IL-1 receptor (IL-1R1). Although IL-1A Alpha is cell associated and IL-1B Beta is secreted, they have nearly identical biological activity in that they induce adhesion molecule expression on epithelial cells, control fever induction, and play a role in arthritis and septic shock. Signaling activated by the IL-1R1 promotes these activities through a MYD88 signaling pathway similar to those associated with Toll receptors. Recombinant human IL-1B Beta is a non-glycosylated single chain 17,376 Da protein containing 153 amino acid residues.
- Formulation:
- 0.01 M Sodium Phosphate, pH 7.5
- Immunogen:
- IL1B
- Physical State:
- Lyophilized
- Purity:
- >97%
- Shipping Conditions:
- Ambient
- Specificity:
- Recombinant protein corresponding to amino acids 1 to 153 of mature human Interleukin-1beta (IL-1B Beta). Purity is greater than 97% as determined by reducing and non-reducing SDS-PAGE and by analytical RP-HPLC, each against a known standard.
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=009-001-301
