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Proteins and Peptides

Bovine Collagen Type I

Product Sizes
500 ug
£327.00
001-001-103-500UG
About this Product
SKU:
001-001-103
Additional Names:
COL1A1|Type I collagen, collagen 1, bovine collagen, Alpha 1 type I collagen, Alpha 2 type I collagen, COL1A1, COL1A2, Collagen alpha-1(I) chain, Collagen alpha-2 (I) chain
Application:
ELISA, Immunohistochemistry, Immunoprecipitation, SDS-PAGE, Western Blot
Buffer:
0.5 M Acetic Acid
CE/IVD:
RUO
Concentration:
1 mg/ml
Extra Details:
Bovine Collagen Type I is one of a family of proteins found particularly in the flesh and connective tissues of mammals (approximately one-third of the body's total protein). Over two dozen types of collagen have been described; Type I is the most abundant form in the body. Collagen Type I is found in scar tissue, tendons, the skin, arterial walls, the corneas, muscles, cartilage, and in the organic parts of bones and teeth. Bovine Collagen Type I is ideal for investigators involved in extracellular matrix proteins and osteoporosis.
Formulation:
0.5 M Acetic Acid
Immunogen:
COL1A1
Physical State:
Liquid
Shipping Conditions:
Blue Ice
Specificity:
Bovine Collagen Type 1 has been prepared from Bovine Placenta and is chromatographically and immunologically pure. Bovine Collagen Type 1 reacts with anti-Collagen Type I. Reaction with Rockland's anti-Collagen II, III, IV, V or VI is negligible.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Native
Aggf1 interacts with and modulates SMAD7 activity. (D) Primary HSCs were infected with Ad-V or Ad-AGGF1 and then transfected with either siRNA targeting SMAD7 or scrambled siRNA (SCR). Expression of fibrogenic genes was examined by Western and qPCR (not shown). Figure 4. PMID: 26850475.
Aggf1 suppresses liver fibrosis following injury in mice. (B) C57/BL6 mice were injected via tail vein adenovirus carrying either Aggf1 expression vector (Ad-AGGF1) or an empty vector (Ad-V) followed by CCl4 injection to induce liver injury. Expression of fibrogenic genes was examined by Western and qPCR (not shown). Figure 2. PMID: 26850475.
SDS-PAGE Results of Bovine Collagen Type I. Lane 1: Bovine Collagen Type I -Reduced [10ug]. Lane 2: Opal Prestained Molecular Weight Marker (p/n MB-210-0500) Lane 3: Bovine Collagen Type I -Non-Reduced [10ug]. 4-20% Gel, Coomassie Stained.
C57/BL mice were injected peritoneally with chaetocin (25mg/kg) or DMSO 2 days prior to the LAD procedure. The mice were sacrificed 4 weeks after the surgery. (B) Expression of pro-fibrogenic genes was examined by Western blotting and qPCR (not Shown). Supplementary Fig.9. PMID: 28361889.