AKT/PKBa Substrate
Product Sizes
500 ug
£259.00
000-000-260-500UG
About this Product
- SKU:
- 000-000-260
- Additional Names:
- AKT1|AKT1, serine/threonine kinase, apoptosis inhibitor substrate peptides, blocking peptide, control peptide
- Application:
- Western Blot
- Buffer:
- None
- CE/IVD:
- RUO
- Concentration:
- 1 mg/ml
- Extra Details:
- Akt is a serine/threonine kinase that enhances cell proliferation and inhibits apoptosis when activated. Akt associates with PI(3,4,5)P3) at the cell membrane through its pleckstrin homology domain and is activated through phosphorylation. 3-Phosphoinositide-dependent kinase-1 (PDK1) has been shown to first phosphorylate Akt at Thr308, then a second kinase phosphorylates Akt at position Ser473. In turn, Akt phosphorylates a host of proteins including the proapoptotic proteins BAD and pro-caspase-9, GSK3, p21WAF1, MDM2, and the forkhead (FKHR) family of transcription factors.
- Immunogen:
- AKT1
- Physical State:
- Lyophilized
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Specificity:
- Greater than 98% specific peptide by HPLC analysis
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Substrates
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=000-000-260
