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Antibodies

CD4; Mouse (T-Cell Marker) Antibody

Product Sizes
100 ug
£671.00
RTM1-2009-P1ABX-100UG
About this Product
SKU:
RTM1-2009-P1ABX
Additional Names:
T-cell differentiation antigen L3T4 | T-cell surface antigen T4/Leu-3
Application:
ELISA, Flow Cytometry, Immunofluorescence
translate.label.attr.clone:
GK1.5
Clonality:
Monoclonal
Extra Details:
CD4 is a member of the Ig superfamily; primarily expressed on most thymocytes; a subset of T cells; and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase; lck. CD4 is expressed by the majority of thymocytes; most helper T cells; a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally.This antibody blocks helper T cell responses to MHC class II antigens; including cytolysis; proliferation; allogeneic B cell help; and release of lymphokines.
Host:
Rat
Immunogen:
Mouse CTL clone V4
Isotype:
IgG2b
Molecular Weight:
55kDa
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody