CD40; Mouse Antibody
Product Sizes
20 ug
£364.00
RTM1-2005-P0-20UG
About this Product
- SKU:
- RTM1-2005-P0
- Additional Names:
- B-cell surface antigen CD40 | Bp50 | CD40L receptor
- Application:
- Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- FGK45.5
- Clonality:
- Monoclonal
- Extra Details:
- Upon binding to its ligand CD154; CD40 acts as a costimulatory molecule for the activation of B cells; dendritic cells; monocytes; and other APCs. CD40 plays roles in B cell activation; differentiation; proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4.5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells; producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes.
- Host:
- Rat
- Immunogen:
- Purified recombinant Mouse CD40 fusion protein
- Isotype:
- IgG2a
- Molecular Weight:
- 48kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=126429
