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Antibodies

Recombinant Pan-HLA-II (DP; DQ; DR) Antibody

Product Sizes
20 ug
£364.00
RBM4-8311-P0-20UG
About this Product
SKU:
RBM4-8311-P0
Additional Names:
HLA class II histocompatibility antigen; DP(W4) beta chain | MHC class II antigen DPB1
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
HLA-Pan/8311R
Clonality:
Monoclonal
Extra Details:
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens; HLA-DP; -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36kDa) and a beta chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes; monocytes; macrophages; and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six alpha and ten beta chain genes. Three loci; DR; DQ and DP; encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They; therefore; have a critical role in the initiation of the immune response.
Host:
Rabbit
Immunogen:
Priess human B cell line
Isotype:
IgG
Molecular Weight:
33-35kDa
Research Area:
Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody