HPV16 E1^E4 (Human Papilloma Virus 16) Antibody
Product Sizes
100 ug
£671.00
MSM9-3066-P1-100UG
About this Product
- SKU:
- MSM9-3066-P1
- Additional Names:
- E1^E4
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- HPV16 E1/E4
- Clonality:
- Monoclonal
- Extra Details:
- The human papilloma virus (HPV) family of DNA tumor viruses includes HPV16; a "high-risk" sexually-transmitted HPV that can lead to cervical; anal; vulvar; head; neck; and penile cancer. The HPV16E1/E4 protein is expressed abundantly in cells supporting viral DNA amplification but is lost during malignant progression. HPV16E1/E4 causes G2 cell cycle arrest by associating with and preventing the nuclear entry of Cdk1/cyclin B1 complexes. HPV16E1/E4 also interacts with cyclin A and Cdk2 during the G2 phase of the cell cycle; and this association may increase the efficiency with which HPV16E1/E4 is able to prevent mitotic entry. HPV16E1/E4 also associates with keratin intermediate filaments and causes the network to collapse.
- Host:
- Mouse
- Immunogen:
- Recombinant human HPV16 E1/E4 fragment (aa 36-41).
- Isotype:
- IgG1
- Molecular Weight:
- 16kDa
- Research Area:
- Cancer; Infectious Disease; Ovarian Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=126274
