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Antibodies

Cytokeratin 8/18 Antibody

Product Sizes
100 ug
£671.00
MSM7-770-P1-100UG
About this Product
SKU:
MSM7-770-P1
Additional Names:
Cytokeratin-8 | Keratin-8 | Type-II keratin Kb8
Application:
Immunohistochemistry
translate.label.attr.clone:
C-43 + DC10
Clonality:
Monoclonal
Extra Details:
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium; for example thyroid; female breast; gastrointestinal tract; respiratory tract; and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.
Host:
Mouse
Immunogen:
Keratin preparation from a human carcinoma (C-43); PMC-42 human breast carcinoma cells (DC10)
Isotype:
IgG1
Molecular Weight:
52.5kDa (CK8); 45kDa (CK18)
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody