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Antibodies

Pan-Cadherin Antibody

Product Sizes
100 ug
£671.00
MSM2-8020-P1-100UG
About this Product
SKU:
MSM2-8020-P1
Additional Names:
CAM 120/80 | Epithelial cadherin | Uvomorulin
Application:
Immunohistochemistry
translate.label.attr.clone:
Pan-CAD/8020
Clonality:
Monoclonal
Extra Details:
Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins; E-; N- and P-cadherin; consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity; transmembrane domains and carboxy terminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins; such as β-catenin; to regulate cadherin function. Members of this family of adhesion proteins include rat cadherin K (and its human homolog; cadherin 6); R-cadherin; B-cadherin; E/P cadherin and cadherin-5.
Host:
Mouse
Immunogen:
Recombinant fragment of human C-terminal of Pan-Cadherin (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
120 kDa
Research Area:
Bladder Cancer; Colon Cancer; Immunology; Infectious Disease; Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody