Cytokeratin 7/17 Antibody
Product Sizes
20 ug
£364.00
MSM14-949-P0-20UG
About this Product
- SKU:
- MSM14-949-P0
- Additional Names:
- Cytokeratin-7 | Keratin-7 | Sarcolectin | Type-II keratin Kb7
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- C-46
- Clonality:
- Monoclonal
- Extra Details:
- It recognizes intermediate filament proteins (IFP's) of 55kDa and 46kDa; which are identified as cytokeratin 7 and Cytokeratin 17 respectively. On formalin-fixed; paraffin embedded sections; C-46 reacts with keratin 7 only. Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation; which is directly applicable to the characterization of malignant tumors. Cytokeratin 7 is a basic cytokeratin; which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Cytokeratin 7 is expressed in the epithelial cells of ovary; lung; and breast but not of colon; prostate; or gastrointestinal tract. Cytokeratin 17 is expressed in epithelial cells of various origins; such as bronchial epithelial cells and skin appendages. Cytokeratin 17 antibody marks basal cell differentiation.
- Host:
- Mouse
- Immunogen:
- Cytoskeletal preparation from HeLa cells (human cervical carcinoma cells)
- Isotype:
- IgG1
- Molecular Weight:
- 55kDa (CK7); 46kDa (CK17)
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=125706
