PNL2 (Melanoma Associated Antigen) Antibody
Product Sizes
100 ug
£671.00
MSM1-894-P1-100UG
About this Product
- SKU:
- MSM1-894-P1
- Application:
- Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- PNL2
- Clonality:
- Monoclonal
- Extra Details:
- Anti-PNL2 is a novel monoclonal antibody; which has recently been introduced as an immunohistochemical reagent to stain melanocytes and tumors derived therefrom. The antigen recognized by PNL2 is different from Melan A and gp100. Its epitope is not destroyed by digestion with neuraminidase i.e. its epitope id not glycosylated. Anti-PNL2 may be most useful because of its high sensitivity for metastatic melanoma (87%); as opposed to 76% for anti-HMB45 and 82% for anti-MART-1. Anti-PNL2 labels intra-epidermal nevi while the dermal component of compound nevi are largely non-reactive with anti-PNL2. Antibodies against PNL2; MART-1 (Melan A) and HMB45 stain most clear cell sarcoma cells and a few cells in angio-myolipomas and lymphangioleiomyomatosis. Anti-PNL2 is a useful antibody for the identification of melanomas and clear cell sarcomas. Differential diagnosis is aided by the results from a panel of antibodies; including antibodies against HMB45; MART-1; tyrosinase; and MiTF.
- Host:
- Mouse
- Immunogen:
- Melanocyte antigen
- Isotype:
- IgG1
- Molecular Weight:
- 100kDa and <10kDa)|Multiple (160kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=125644
