Plasma Cell Marker Antibody
Product Sizes
100 ug
£671.00
MSM1-47-P1ABX-100UG
About this Product
- SKU:
- MSM1-47-P1ABX
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- LIV3G11; same as 7B18
- Clonality:
- Monoclonal
- Extra Details:
- It recognizes an intra-cytoplasmic antigen; which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells. Plasma cells; which are large lymphocytes derived from an antigen-specific B cell; secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC); consuming an offending pathogen; which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm; their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This MAb superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed; paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Note that this MAb is not suitable for staining frozen tissues.
- Host:
- Mouse
- Immunogen:
- Pancreatic cancer-related mucin
- Isotype:
- IgG2a
- Molecular Weight:
- Not Known
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=125586
