Recombinant TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) Antibody
Product Sizes
100 ug
£671.00
9966-MSM3-P1ABX-100UG
About this Product
- SKU:
- 9966-MSM3-P1ABX
- Additional Names:
- TNF ligand-related molecule 1 | Vascular endothelial cell growth inhibitor
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- rVEGI/1283
- Clonality:
- Monoclonal
- Extra Details:
- VEGI is an anti-angiogenic cytokine that belongs to tumor necrosis factor superfamily; member 15 (TNFSF15). This protein is abundantly expressed in endothelial cells; but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases; and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation; and thus may function as an angiogenesis inhibitor. Reduced expression of VEGI has been reported as a marker of poor prognosis in breast cancer.
- Host:
- Mouse
- Immunogen:
- Recombinant human full-length VEGI protein
- Isotype:
- IgG1
- Molecular Weight:
- 22kDa
- Research Area:
- Cardiovascular; Cytokine Signaling; Immuno Oncology; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=125345
