Y14 / RBM8A Antibody
Product Sizes
20 ug
£364.00
9939-MSM2-P0-20UG
About this Product
- SKU:
- 9939-MSM2-P0
- Additional Names:
- Binder of OVCA1-1 | RNA-binding motif protein 8A | RNA-binding protein Y14 | Ribonucleoprotein RBM8A
- Application:
- Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- PCRP-RBM8A-1B4
- Clonality:
- Monoclonal
- Extra Details:
- Y14 Antibody is a high quality monoclonal Y14 antibody (also designated Y14 antibody) suitable for the detection of the Y14 protein of mouse; rat; human and Xenopus laevis origin. Y14 Antibody (4C4) is available as both the non-conjugated anti-Y14 antibody form; as well as multiple conjugated forms of anti-Y14 antibody; including agarose; HRP; PE; FITC and multiple Alexa Fluor conjugates. The exon junction complex (EJC) is a multiprotein complex that assembles approximately 20-24 nucleotides upstream of exon-exon junctions in pre-mRNAs. It is involved in mRNA export; cytoplasmic localization; and nonsense-mediated mRNA decay. Members of the EJC include Y14; Aly/REF; Magoh; RNPS1; SRm160; and DEK. Aly/REF; Magoh; and Y14; identified as RBM8 in mouse and rat; make up the core of the EJC; and these proteins remain stably bound to spliced mRNAs in the cytoplasm until they are translated. Therefore; Y14; Aly/REF; and Magoh have the ability to communicate to the cytoplasm the processing history of the mRNA; including the position of the removed introns. The gene encoding human Y14 encodes three transcripts. Y14 is a ubiquitously expressed protein. Although Y14 shuttles to the cytoplasm; it is predominantly detected in the nucleus and is co-localized with oskar mRNA at the posterior pole of the cell.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human RBM8A protein
- Isotype:
- IgG1
- Molecular Weight:
- 24kDa
- Research Area:
- Developmental Biology; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=125316
