CDC5L Antibody
Product Sizes
100 ug
£671.00
988-MSM2-P1-100UG
About this Product
- SKU:
- 988-MSM2-P1
- Additional Names:
- Pombe cdc5-related protein
- Application:
- Flow Cytometry, Immunohistochemistry
- translate.label.attr.clone:
- PCRP-CDC5L-2C6
- Clonality:
- Monoclonal
- Extra Details:
- Cdc5L (cell division cycle 5-like protein; pombe Cdc5-related protein) is a DNA-binding protein encoded by the human gene CDC5L. Cdc5L contains two HTH Myb-type DNA-binding domains and may shuttle between cytoplasm and nucleus. It is involved in cell cycle control and may act as a transcription activator. Cdc5L is a spliceosomal protein that is highly conserved across species. It belongs to the group of proteins that comprise the core of spliceosomal complexes and are essential for pre-mRNA splicing. Cdc5L is involved in the second catalytic step of pre-mRNA splicing; which involves cleavage at the 3' splice site and the ligation of the exons. This process releases the intact intron lariat. A chromosomal aberration involving Cdc5L is found in multicystic renal dysplasia. This aberration is caused by a translocation (t 6;19;p21;q13.1) with USF-2.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 1-148) of human CDC5L protein (exact sequence is proprietary)
- Isotype:
- IgG2a
- Molecular Weight:
- 92kDa
- Research Area:
- Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=127307
