Cdk1 / p34cdc2 Serine-Threonine Kinase Antibody
Product Sizes
100 ug
£671.00
983-MSM3-P1-100UG
About this Product
- SKU:
- 983-MSM3-P1
- Additional Names:
- Cell division control protein 2 homolog | Cell division protein kinase 1 | p34 protein kinase
- Application:
- Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- A17.1.1
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a 34kDa protein (cdk1); identified as p34cdc2 (a catalytic subunit of Maturation Promoting Factor). Its epitope maps near the C-terminus of the protein and its core is thought to be LGTPNNEV (aa220-227 in murine cdc2). It shows no cross reaction with cdk2 p32. It supports the kinase activity. p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is a serine/threonine kinase; which is activated by cyclin; by dephosphorylation of tyrosine residues. p34cdc2 is inactivated by a tyrosine kinase. This MAb reportedly inhibits the activation of p34cdc2 kinase by cyclins.
- Host:
- Mouse
- Immunogen:
- C-Terminal 2/3rds of Xenopus cdc2 expressed in E.coli
- Isotype:
- IgG2a
- Molecular Weight:
- 34kDa
- Research Area:
- Ovarian Cancer; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=125288
