Recombinant CD151 Antibody
Product Sizes
100 ug
£671.00
977-RBM5-P1-100UG
About this Product
- SKU:
- 977-RBM5-P1
- Additional Names:
- GP27 | Membrane glycoprotein SFA-1 | Platelet-endothelial tetraspan antigen 3 | Tetraspanin-24
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- CD151/9297R
- Clonality:
- Monoclonal
- Extra Details:
- CD151 is involved in a wide variety of cell biological processes; including cell adhesion and the transport of integrins via vesicles. The human CD151 gene maps to chromosome 11p15.5 and encodes a 253 amino acid protein; which belongs to the tetraspan (4TM) superfamily. CD151 can associate with several integrin chains including β1; β3; β4; α2; α3; α5 and α6 integrins. CD151 may provide a framework for the spatial organization of both type I and type II hemidesmosomes; which are specialized junctional complexes that function as cell attachment sites for binding to basement membranes. CD151 RNA transcript (1.6 kb) can be detected in MO7e cells; bone marrow stromal cells; C11 endothelial cells; HUVEC and several myeloid leukemia cell lines; however; no transcript is detected in brain and the lymphoblastoid cell lines MOLT-4 and BALM-1. Leu 149-Glu 213 of CD151 is the interface through which Integrin α3/β1 can bind. CD151 can enhance cell motility; invasion and metastasis of cancer cells in a focal adhesion kinase dependent manner.
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human CD151 protein
- Isotype:
- IgG
- Molecular Weight:
- 28-32kDa
- Research Area:
- Mesenchymal Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=127275
