CD79a (B Cell Marker) Antibody
Product Sizes
100 ug
£671.00
973-MSM3-P1-100UG
About this Product
- SKU:
- 973-MSM3-P1
- Additional Names:
- Ig-alpha | MB-1 membrane glycoprotein | Membrane-bound immunoglobulin-associated protein | Surface IgM-associated protein
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- JCB117 + HM47/A9
- Clonality:
- Monoclonal
- Extra Details:
- A disulphide-linked heterodimer; consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides; is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage; early in maturation; and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type; in B cell lines; B cell lymphomas; and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20; but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.
- Host:
- Mouse
- Immunogen:
- A synthetic peptide corresponding to aa 202-216 (GTYQDVGSLNIADVQ) of human CD79a protein (JCB117 and HM47/A9).
- Isotype:
- IgG1
- Molecular Weight:
- 44kDa
- Research Area:
- B Cell Markers; Cancer; Hematopoietic Stem Cells; Immunology; Infectious Disease; Mesenchymal Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=125197
