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Antibodies

CD74 (B-Cell Marker) Antibody

Product Sizes
20 ug
£364.00
972-MSM1X-P0-20UG
About this Product
SKU:
972-MSM1X-P0
Additional Names:
HLA-DR antigens-associated invariant chain | Ia antigen-associated invariant chain
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry
translate.label.attr.clone:
SPM523
Clonality:
Monoclonal
Extra Details:
CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells; such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage); macrophages; and monocytes; and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas; but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).
Host:
Mouse
Immunogen:
SU-DHL-4 lymphoma cells
Isotype:
IgG1
Molecular Weight:
33-41kDa
Research Area:
B Cell Markers; Cancer; Cardiovascular; Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody