CD74 (B-Cell Marker) (Transcription Regulator) Antibody
Product Sizes
100 ug
£671.00
972-MSM14-P1-100UG
About this Product
- SKU:
- 972-MSM14-P1
- Additional Names:
- HLA-DR antigens-associated invariant chain | Ia antigen-associated invariant chain
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- CLIP/7194
- Clonality:
- Monoclonal
- Extra Details:
- It recognizes a protein of ~35kDa; identified as CD74 (Workshop IV). CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells; such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage); macrophages; and monocytes; and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas; but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human CD74 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 33-41kDa
- Research Area:
- B Cell Markers; Cardiovascular; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=127693
