Recombinant CD63 (Late Endosomes Marker) Antibody
Product Sizes
100 ug
£671.00
967-RBM24-P1ABX-100UG
About this Product
- SKU:
- 967-RBM24-P1ABX
- Additional Names:
- Granulophysin | Lysosomal-associated membrane protein 3 | Lysosome integral membrane protein 1 | Melanoma-associated antigen ME491 | OMA81H | Ocular melanoma-associated antigen | Tetraspanin-30
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- LAMP3/8705R
- Clonality:
- Monoclonal
- Extra Details:
- This MAb recognizes protein of 26kDa-60kDa; which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets; monocytes and macrophages; and is weakly expressed on granulocytes; T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9; CD37 and CD53; which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human CD63 protein (recognizes extracellular epitope)
- Isotype:
- IgG
- Molecular Weight:
- 26kDa (core protein); 30-60kDa (glycosylated)
- Research Area:
- Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=129937
