CD53 (TSPAN25) Antibody
Product Sizes
100 ug
£671.00
963-MSM1-P1ABX-100UG
About this Product
- SKU:
- 963-MSM1-P1ABX
- Additional Names:
- Cell surface glycoprotein CD53 | Tetraspanin-25
- Application:
- Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- 63-5A3
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 33-55kDa; identified as CD53 (Workshop V; Code CD53.1). CD53 is expressed on monocytes; and macrophages; granulocytes; dendritic cells; osteoblasts and osteoclasts; NK cells; and on T- and B-cells from every stage of differentiation but is absent from platelets; erythrocytes; and non-haemopoietic cells. CD53 is a member of a family of tetraspan transmembrane proteins; including CD9; CD37; CD63; CD81; and CD82. It associates with integrins; MHC class II molecules; and a tyrosine phosphatase and plays a role in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. Defects of CD53 expression on neutrophils appear to be related with recurrent infectious diseases. Cross-linking CD53 using CD53 antibodies led to cytoplasmic calcium fluxes in B cells; monocytes; and granulocytes and activation of the monocyte oxidative burst.
- Host:
- Mouse
- Immunogen:
- Human Sezary cells
- Isotype:
- IgG2b
- Molecular Weight:
- 33-55kDa
- Research Area:
- Cardiovascular; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=124981
