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Antibodies

CD47 / IAP (Integrin Associated Protein) Antibody

Product Sizes
100 ug
£671.00
961-MSM1-P1ABX-100UG
About this Product
SKU:
961-MSM1-P1ABX
Additional Names:
Antigenic surface determinant protein OA3 | Integrin-associated protein | Protein MER6
Application:
Flow Cytometry, Immunofluorescence, Western Blot
translate.label.attr.clone:
B6H12.2
Clonality:
Monoclonal
Extra Details:
This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47; originally named integrin-associated protein (IAP); is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets; and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
Host:
Mouse
Immunogen:
Intact CD47 Purified from placenta
Isotype:
IgG1
Molecular Weight:
~50kDa
Research Area:
Cardiovascular; Immune checkpoint; Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody