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Antibodies

Recombinant CD44 / HCAM (Cancer Stem Cell Marker) Antibody

Product Sizes
20 ug
£364.00
960-RBM18-P0-20UG
About this Product
SKU:
960-RBM18-P0
Additional Names:
CDw44 | Epican | Extracellular matrix receptor III | GP90 lymphocyte homing/adhesion receptor | HUTCH-I | Heparan sulfate proteoglycan | Hermes antigen | Hyaluronate receptor | Phagocytic glycoprotein 1 | Phagocytic glycoprotein I
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
HCAM/2875R
Clonality:
Monoclonal
Extra Details:
Recognizes a cell surface glycoprotein of 80-95kDa (CD44) on lymphocytes; monocytes; and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. This MAb selectively interferes with lymphocyte binding to lymph node; mucosal and synovial endothelium. The CD44 family of glycoproteins exists in a number of variant isoforms; the most common being the standard 85-95kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v); which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.
Host:
Rabbit
Immunogen:
Stimulated human leukocytes
Isotype:
IgG
Molecular Weight:
80-95kDa
Research Area:
Articular Cartilage Extracellular Matrix; Cardiovascular; Cytokine Signaling; Hematopoietic Stem Cells; Immunology; Mesenchymal Stem Cell Differentiation; Neural Stem Cells
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody