CREB5 / CRE-BPa Antibody
Product Sizes
20 ug
£364.00
9586-MSM1-P0-20UG
About this Product
- SKU:
- 9586-MSM1-P0
- Additional Names:
- cAMP-response element-binding protein A
- Application:
- Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- PCRP-CREB5-1G8
- Clonality:
- Monoclonal
- Extra Details:
- The ATF/CREB family consists of a series of transcription factors that function by binding to the cAMP responsive element (CRE) palindromic octanucleotide; TGACCTCA. The best characterized members of this gene family include CREB-1; CREB-2 (also designated ATF-4); CRE-BPa; LZIP (also designated CREB-3 and Luman); CREM-2; ATF-1; ATF-2; ATF-3; ATF-5; ATF-6 and ATF-7. These transcription factors share terminal leucine zipper dimerization and basic DNA binding domains and are highly variable in their N-termini. Although each of the ATF/ CREB proteins bind CREs in their homodimeric form; they can also bind as heterodimers; both within the ATF/CREB family and with members of the AP-1 transcription factor family. Protein kinase A- mediated CREB phosphorylation induces association with a nuclear protein designated CBP (CREB-binding protein); which may represent a CREB coactivator. CRE-BPa is a nuclear protein that binds DNA as a homodimer but can also form a heterodimer with ATF-2 or Jun.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human CREB5 protein
- Isotype:
- IgG2b
- Molecular Weight:
- 57kDa
- Research Area:
- Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=124802
