Recombinant CD39 / ENTPD1 (Marker of Tumor-specific T cells) Antibody
Product Sizes
20 ug
£364.00
953-MSM4-P0-20UG
About this Product
- SKU:
- 953-MSM4-P0
- Additional Names:
- Ecto-ATP diphosphohydrolase 1 | Ecto-apyrase | Lymphoid cell activation antigen
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- rCD39/8682
- Clonality:
- Monoclonal
- Extra Details:
- CD39; also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENP1); is an integral membrane glycoprotein that acts as an extracellular nucleotide-hydrolyzing enzyme. CD39 inhibits ADP-induced platelet aggregation by hydrolyzing ADP to AMP; and ultimately generating Adenosine. Intracellular CD39 undergoes glycosylation at six N-glycosylation sites and translocates to the membrane in order to be an active enzyme. Alternative splicing gives rise to three CD39 isoforms; vascular; placenta I and placenta II. The placenta I isoform differs at the amino terminus whereas the placenta II isoform is missing amino acids 300-510 at the C-terminus. CD39 is expressed in vascular tissues including placenta; lung; skeletal muscle and kidney; as well as endothelium; smooth muscle; cardiac cells; lymphocytes; such as activated B cells; activated NK cells; macrophages; Dendridic cells and platelets. CD39 may be used as an anti-thrombic agent for pre-treating patients at risk for coronary artery occlusion and thrombic stroke.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human CD39 protein
- Isotype:
- IgG1
- Molecular Weight:
- 70-100 kDa
- Research Area:
- Infectious Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=134352
